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Ozempic should be injected subcutaneously (under the skin) and never into a muscle or vein

Jaclyn Leong, Medical Director of the UCI Health Weight Management Program, at the ObesityHelp 2025 National Conference, where she discussed evidence-based nutrition, resistance training, and integrative strategies to support lean body mass during GLP-1 therapy

This includes individuals with metabolic syndrome, characterized by central adiposity, insulin resistance, dyslipidemia, and hypertension

The medications are more likely to be covered for treatment of diabetes than when prescribed off-label for weight loss, says Banini

Additionally, baseline metabolic health, insulin sensitivity, stomach motility, and concurrent medications affect efficacy and tolerability