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The improvements require ongoing treatment to maintain

Purcell AR, Rodrigo N, Longfield MS, Glastras SJ

Beyond age 18, medical eligibility depends on BMI, metabolic status, and absence of contraindications like personal or family history of thyroid cancer or multiple endocrine neoplasia

[10] [15] These effects are modest compared with medication, but they support overall gut and metabolic health

The mechanism the clinic describes is that MOTS-C works by activating AMPK, a key metabolic pathway involved in glucose utilisation, fat oxidation and insulin sensitivity

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