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Clinical studies provide direct evidence: GLP-1 analogue therapy significantly reduced sCD163 (a marker of inflammatory macrophage activation), independent of changes in body weight, fructosamine, and HbA1c

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p -value 0.0331]), semaglutide (RR 2.3447 [95% CI 1.4134, 3.8898

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That said, the established therapies and pipeline from Novo Nordisk and Eli Lilly are formidable, he adds

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