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Forty-six patients with IgA nephropathy at Kyoto University Hospital who underwent kidney biopsy between 2014 and 2018 were recruited (Table 1 and Supplemental Figure 1)

Previous in vivo and in vitro studies have revealed a role for NGF in the activation of the antioxidant response in the CNS in regions such as the cerebellum (Pan and Perez-Polo, 1993