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Responsible research use where legally permitted implies baseline and follow-up bloodwork (including IGF-1 and fasting glucose), conservative dosing, and oversight by a knowledgeable clinician

Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial

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This inability is probably due to the function of glutamine metabolism, which provides both carbon and nitrogen for cellular biogenesis

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