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Diabetologia 48 , 16211626 (2005)
In a model of erectile dysfunction in diabetic rats, SAC restored electrically-induced penile erection by stimulating eNOS activity and inhibiting the expression of NADPH oxidase (Nox) responsible for ROS overproduction (33)
In the first half-reaction, Cys248 attacks GSSH to form an enzyme-bound cysteine persulfide intermediate, releasing GSH
The results were very impressive
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