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Trial The STEP-HFpEF Trial Conducted at 96 sites in 13 countries in Asia, Europe, North America, and South America Randomized 529 patients between March 2021 and March 2022
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They include increased blood pressure, tachycardia (heart rate over 100 beats per minute), pulmonary hypertension, disease of the heart valves, or even events related to ischemia (loss of blood flow) to the heart or other organs
For medicines: For risks and side effects, read the package leaflet and ask your doctor or pharmacist
It mainly stimulates insulin secretion and inhibits the release of glucagon by binding to receptors on pancreatic beta cells, thus helping to lower blood glucose levels
Molecular docking Molecular docking of ursolic acid, oleanolic acid and betulinic acid with FXR was carried out using AutoDock QVina-W
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