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The C718T polymorphism in the 3-untranslated region of glutathione peroxidase-4 gene is a predictor of cerebral stroke in patients with essential hypertension

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Therefore, Boggio et al

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NLRP3 inflammasome activation requires two signals: a priming signal (activating the NF-B pathway) and an activation signal (mediated through mechanisms including potassium efflux, mitochondrial dysfunction, and ROS generation) (79, 80)

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